In the unique landscape of immunology research in New Zealand, this article explores the collaborative networks spanning the two main islands, through a conversation with Associate Professor Joanna Kirman and Dr. Robert Weinkove. The discussions delve into their dynamic collaborations with countries like Asia, Australia, and the United States from their labs at the University of Otago and the Malaghan Institute respectively, provides insight into the translational research landscape of New Zealand, and the integration of Māori culture into all aspects of scientific research and clinical practise. Kirman’s work in understanding immunological memory in tuberculosis and Weinkove’s research in cancer immunotherapies, particularly CAR-T cells, are highlighted. The natural beauty and accessibility of New Zealand supports it’s research diversity.

Emeritus Professor Margaret Baird forged a luminary career for her pioneering research investigating the role of dendritic cells (DCs) in cancer and infectious diseases, as an inspirational lecturer at the University of Otago and a role model to many. In this article celebrating the 100-year anniversary of ICB, we discuss Margaret’s career and life journey through the eyes of her family and co-authors, as we explore her many publications in ICB and beyond.

The establishment of in vitro models plays a vital role in understanding and investigating pulmonary fibrosis (PF) at the cellular and molecular levels. In this paper, we conduct a literature review and provide an analysis of various cellular models used in scientific experiments, along with their applications in understanding the pathogenesis of PF. Our studies indicate that a comprehensive understanding of PF should not be based on a single cell type or organ, but on a multi-organ, multi-level, and multi-perspective approach. Primary cells demonstrate superior cell growth characteristics and gene expression profiles. However, challenges such as limited availability, difficulties in maintenance, inability for continuous propagation, and susceptibility to phenotype loss over time significantly restrict their utility in scientific research. On the other hand, replacement cell lines can be easily obtained, cultured, and continuously propagated, but their phenotypic characteristics are somewhat different compared to primary cells. In vitro co-culture models offer a more practical and precise means to elucidate the intricate interactions between cells, tissues, and organs. Therefore, when constructing pathology models of PF, researchers should carefully consider the advantages, limitations, and relevant mechanisms associated with different cell models for selection according to the research objectives.

Laboratory science sometimes looks like it’s built exclusively for young people, but if you look closely, you’ll find another group of scientists waiting to join your lab: those of us who didn’t quite launch our careers on a normal trajectory. Welcoming a second-career scientist into your lab takes time and resources, but may just be well worth it. Here’s what one second-career scientist wants you to know about supporting second careers in immunology.