Nowadays apparently harmless Candida species especially rare ones, cause a rising number of infections. We report the first case of conjunctivitis due to Candida metapsilosis obtained from the eye discharge of 40-day-old girl with congenital heart disease admitted in the ICU. The isolate was resistant to fluconazole, anidulafungin and micafungin.

Abstract: Duplicity of the appendices are very rare. A 32-year-old man presented with type B2 duplicity of the appendix and acute appendicitis. An appendectomy was done for both. Intraoperative incidental finding, is the only chance to avoid missing appendix duplicity and appendicectomy should be done for both.

Total anomalous pulmonary venous connection is a rare congenital anomaly, and has four anatomical subtypes of which the mixed type represents diagnostic and therapeutic challenge. Herein, we present a rare case of obstructed mixed type total anomalous pulmonary venous connection with successful surgical repair

Metastatic laryngeal cancers are rare and usually indicate advanced disease once they are present; we described a case of a 60 years old male patient with stage IV colorectal cancer (CRC) who presented to our clinic with dysphonia; further workups showed metastatic CRC.

Recently spontaneous tension pneumomediastinum (PTM), pneumothorax (PT), and subcutaneous emphysema (SE) were reported as infrequent complications in COVID-19 patients. Early diagnosis and treatment could save the patients since these complications are related to poor prognosis and prolonged hospitalization. Here we report these complications in an Iranian patient.

A man in his 50s with no significant past medical history developed subarachnoid hemorrhage due to ruptured left middle cerebral artery aneurysm. 9th hospital day, he experienced a ruptured visceral aneurysm with segmental arterial mediolysis, and we successfully treated with transarterial embolization using metallic coils.

Infective endocarditis rarely presents with cutaneous manifestations due to earlier diagnosis and treatment. We present a case of a middle-aged male patient presenting with an erythematous papular rash in the upper extremities and left knee, further progressing into painful ulcers.

Coffin-Siris syndrome is a rare disorder which can be difficult to recognize. A broad spectrum of nonspecific clinical features is associated with Coffin-Siris syndrome and expression of these features is diverse. We describe two cases with Coffin-Siris syndrome with mutations in the ARID1A gene, with dissimilar presentation and clinical course.

Herein, we report a case of VAIHS with atypical clinical presentation of perianal abscess, fistula fever and bicytopenia including pathogenic ADA2 mutation suggesting that ADA2 deficiency be considered as a differential diagnosis of enlarging cutaneous abscess with no evidence of wound healing in the setting of leukopenia and neutropenia.

Symptomatic cardiac involvement of malignant lymphoma is rare. Silent invasion of malignant lymphoma makes it difficult to diagnose it in the early phase of clinical course. We describe a case with cardiac involvement of diffuse large B-cell lymphoma presenting various types of arrythmias that were not diagnosed until autopsy.

Open dislocation of the ankle and Epstein's superior type of hip dislocation are rare orthopedic injuries. We reported a case of 50 years gentleman with a combination of these two rare orthopedic emergencies without any associated fracture with the newly reported mechanism and management to save limb and its function.

A narrative review based on the case of a patient presenting an atypical symptomatology of an atraumatic splenic rupture induced by rivaroxaban. An emergency splenectomy had to be performed. This complication is rare but increasing since the popularity of direct oral anticoagulants and the diagnosis is often delayed.

We present the rare case of a 71 year old man with intracranial primary dural Hodgkin lymphoma (PDHL). He underwent subtotal resection of the mass, followed by adjuvant chemotherapy and consolidative radiotherapy, with no recurrence at 5 years follow up.

Urethral duplication is uncommon with few cases reported in the literature. We report a case in which a patient presented with discharge from proximal part of penis since childhood and recent history of infection. The diagnosis of pre-pubic sinus was made and complete excision of the sinus tract was done.

The two cases we present are the first to demonstrate novel manifestations of COVID-19- related interaction between the liver and the immune system in pediatric patients. Written informed consent was obtained from the parent/guardian to publish this report in accordance with the journal’s patient consent policy.

Chylous ascites following trauma in children is very rare, and to the best of our knowledge, there are very few reports in this regard. Here, we report a 7-year-old girl who was referred to our center with CA after a car accident.

The author's intent is to bring one such case to focus wherein just mere lack of knowledge and casual approach towards one's own health having undiagnosed underlying blood coagulation disorder led to catastrophic sequence of events, leaving behind a cautionary learning tale from a loss of life.

A healthy 48-years-old male patient was referred to our department to take radiographs of a displaced implant. Upon radiographic evaluation, it was unveiled that the implant has migrated to the nasal cavity and is trapped under the middle concha. The implant was removed under endoscopy through the right nostril.