Combined large cell neuroendocrine carcinoma (LCNEC) and squamous cell carcinoma (SCC) of the H&N is exceptionally rare. We present the case of combined p16 negative SCC and LCNEC of the oropharynx treated with combination chemotherapy. This is the third reported case of combined neuroendocrine carcinoma and SCC of the oropharynx.

COVID 19 has created one of the world’s worst pandemics and is associated with various life-threatening complications, such as Cytomegalovirus (CMV) co-infection. We present a life-threatening CMV viremia co-infection in a none-immunocompromised COVID 19 patient to highlight our management approach and a comprehensive literature review.

A 75-year-old male presented with an immediately threatened grade IIb acute ischemia of the left leg due to thrombosis of a femoro-infrapopliteal prosthetic bypass graft. After an urgent Computed Tomography Angiography, an urgent graft thrombectomy was performed using a 5 Fr Fogarty catheter, which had a troublesome distal passage.

We described a rare case of nadroparin-induced skin necrosis with thrombocytopenia.LMWH therapy is used in thrombosis prophylaxis, it is important to recognize that skin necrosis can be a part of HIT early in its course and change heparin or LMWH to non-heparin anticoagulants such as director thrombin III inhibitors.

Bronchogenic Cysts are embryologic malformations of the foregut and are rarely found head and neck region. Here we present a case of an upper scapular/lower posterior neck cystic mass which was initially suspicious for lymphatic malformation but confirmed by pathology to be a ectopic bronchogenic cyst.

Injectable bleomycin is infrequently used for recalcitrant warts despite its efficacy, acceptable safety profile, and high patient satisfaction compared to other treatment modalities. We present an immunocompromised patient with a large recalcitrant wart successfully treated with intralesional bleomycin to provide greater clinical exposure, training, and practice with intralesional bleomycin.

Ectopic origin of the right coronary artery from the left sinus of Valsalva is an extremely rare anomaly of coronary arterial morphology, often incidentally discovered and clinically silent. We, hereunder, experienced a case of ectopic origin of the right coronary artery from the left sinus of Valsalva.

The Duchenne Muscular Dystrophy (DMD) gene variants are associated with the disease phenotypes. The pathogenic mutation, c.2293-1G>C, was detected in DMD gene in the proband and the fetus, which has not been reported in the literature.The minigene expression in vitro confirmed that c.2293-1G>C is responsible of aberrant splicing.

Our patient had previously been diagnosed with Ulcerative colitis. the clinical manifestations of the patient along with laboratory tests such as anti-dsDNA and proteinuria were also positive. Therefore, the clinical manifestation was consistent with SLE. in the following work up monoclonal gammopathy in serum electrophoresis was also detected.

Obstructive uropathy is one of the leading causes of urosepsis. In the patients with severe hydronephrosis, underlying sepsis and renal dysfunction should be treated with caution. Each additional hour of delay in antibiotics administration was found to lower the survival rate.

A case with non-small cell lung cancer exhibited extreme hyperglycemia after lorlatinib treatment, whose adverse effects on hyperglycemia is little known. But, the lorlatinib could be continued by intensifying diabetes treatment, indicating the importance of glucose monitoring during lorlatinib administration, and of adequate intensification of treatment for such hyperglycemia.

Multisystem Inflammatory Syndrome is a rare and novel clinical presentation described during the evolving Covid- 19 pandemic. The condition is usually presenting as a sepsis-like syndrome leading to secondary multiorgan dysfunction post-COVID-19 infection. Although the syndrome has been mainly described in children, rare adults' form has been similarly described.

Psoriasis is a chronic inflammatory disease with characteristic skin manifestations. Several pathogens can cause flare-ups of psoriasis. The risks of skin infections are increased in patients receiving immunomodulators. A patient with chronic psoriasis presented with human papillomavirus infection and anogenital warts and was treated surgically with acceptable results.

COVID-19 has been linked to a number of cutaneous symptoms in COVID-19 patients. Although herpes zoster (HZ) was the first sign of COVID-19 infection in several patients, cases of HZ after COVID-19 vaccination are rare. We report case of 51 years old male with Herpes Zoster after Sinopharm (Vero Cell).

Doege-Potter syndrome leads to severe and sustained symptomatic hypoglycemia and is associated with the solitary fibrous tumor. It is a rare cause and its diagnosis requires a clinical suspicion and other markers such as insulin-like growth factor-II. Here, we describe a case of a patient with intrathoracic tumor and hypoglycemia

Tuberculous (TB) infection remains one of the leading causes of death, especially in developing countries. TB liver involvement is a rare extrapulmonary manifestation of TB and is usually found as a secondary involvement to TB of the lung. Here we are presenting a case of Isolated TB liver abscess.

Non-islet cell tumor hypoglycemia (NICTH) is a rare but severe complication of malignancy. We present the case of 55 year old man who was admitted for severe hypoglycemia. The diagnosis of insulinoma was ruled out. After clinical work-ups, we made the diagnosis of metastatic HCC with production of IGF-2.

Rothmund-Thomson Syndrome is a rare autosomal recessive condition presenting usually in infancy that can be diagnosed based on time of onset, spreading and appearance of the poikiloderma.The purpose of reporting this case is to highlight the clinical approach to a child who presents with the features of poikiloderma.