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Adverse effects related to paediatric influenza vaccination and its influence on vaccination acceptability: A survey study conducted in The Region of Murcia, Spain
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  • Matilde Zornoza Moreno,
  • Jaime Pérez,
  • María Gómez Moreno,
  • María Valcárcel Gómez,
  • Marta Pérez Martínez,
  • Francisca Tornel Miñarro
Matilde Zornoza Moreno
Región de Murcia Consejería de Sanidad
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Jaime Pérez
Región de Murcia Consejería de Sanidad

Corresponding Author:jaimej.perez@carm.es

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María Gómez Moreno
Región de Murcia Consejería de Sanidad
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María Valcárcel Gómez
Región de Murcia Consejería de Sanidad
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Marta Pérez Martínez
Región de Murcia Consejería de Sanidad
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Francisca Tornel Miñarro
Región de Murcia Consejería de Sanidad
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Abstract

Background: During the 2022-23 season, three autonomous communities recommended influenza vaccination for all children between 6 and 59 months. The objective is to evaluate the adverse effects associated with the administered influenza vaccines in the Region of Murcia, as well as their influence on the recommendation of the same to acquaintances or repetition in future seasons. Material and methods: Cross-sectional descriptive study with an online questionnaire sent to the parents of vaccinated minors of 6-23 months of age receiving inactivated intramuscular vaccine (IIV) or 24-59 months of age receiving live-attenuated intranasal vaccine (LAIV). Results: among 4,971 surveys received the most common adverse effect for LAIV and IIV were runny nose (40.90%) and local pain (31.94%) respectively. Sixty percent of adverse effects lasted ≤1 day, and around 10% lasted ≥3 days. The interference of adverse effects with the minor’s daily life was very infrequent (3.32%), as was the need for visiting the medical office (2.68%). Overall, 96.44% of parents would recommend influenza vaccination to friends and relatives after the experience. Only 3.56% would not recommend it, while 1.68% would not vaccinate their child against influenza again. The most frequently cited reason being adverse effects. Conclusions: Our study shows the safety of influenza vaccines. Despite the low impact of adverse effects, they influence some parents in their intention to continue vaccinating or recommending it to acquaintances, which remarks the need to reinforce the information given to parents so that this fact does not influence.
Submitted to Influenza and other respiratory viruses
17 Apr 2024Review(s) Completed, Editorial Evaluation Pending
12 May 2024Editorial Decision: Accept