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Long-term impacts of different dialysis modalities on right ventricular function in patients with end-stage renal disease
  • Duygu Ersan Demirci,
  • Deniz Demirci,
  • Ayça İNCİ
Duygu Ersan Demirci
Antalya Egitim ve Arastirma Hastanesi

Corresponding Author:duygu_ersan@yahoo.com

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Deniz Demirci
Department of Cardiology Istanbul Training and Research Hospital Istanbul Turkey
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Ayça İNCİ
Antalya Egitim ve Arastirma Hastanesi
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Abstract

Background Right ventricular dysfunction is a major cause of heart failure and mortality in end-stage renal disease patients. Scarce data is available regarding the comparison of echocardiographic right ventricular function in end-stage renal disease patients on hemodialysis (HD) and peritoneal dialysis (PD). The aim of the study was to evaluate the long-term impacts of different dialysis modalities on right ventricular function assessed by conventional echocardiography, in end-stage renal disease patients with preserved left ventricular function. Methods The study included 120 patients grouped as follows: PD(n=40), HD with arterio-venous fistula (n=40) and healthy control subjects (n=40). Conventional echocardiography was performed in all patients. A classification of right ventricular function was defined in HD patients by using tricuspid annular plane systolic excursion (TAPSE), right ventricular myocardial performance index (RV-MPI), fractional area change (FAC) and tricuspid lateral annulus systolic velocity (Sa) values. Correlation analysis was performed by using right ventricular dysfunction score, clinical and echocardiographic parameters. Results The mean age of the study population was 51.9±13.1 years and 47.5% were females. TAPSE and Sa velocity were found to be significantly lower and RV-MPI was significantly higher in patients undergoing HD, compared with control and PD patients. Logistic regression analysis showed that HD treatment was an independent risk factor for developing right ventricular dysfunction. Conclusion RV function was impaired in patients undergoing HD compared with patients on PD.
20 May 2022Submitted to Echocardiography
23 May 2022Submission Checks Completed
23 May 2022Assigned to Editor
31 May 2022Reviewer(s) Assigned
30 Jun 2022Review(s) Completed, Editorial Evaluation Pending
03 Jul 2022Editorial Decision: Revise Major
18 Aug 20221st Revision Received
22 Aug 2022Submission Checks Completed
22 Aug 2022Assigned to Editor
22 Aug 2022Reviewer(s) Assigned
24 Aug 2022Review(s) Completed, Editorial Evaluation Pending
03 Sep 2022Editorial Decision: Accept