IntroductionBelly Dancer’s Dyskinesia (BDD), also known as diaphragmatic myoclonus or diaphragmatic flutter, is named for the hallmark clinical finding of repetitive, involuntary, rhythmic twitching of the upper abdomen and diaphragm. The pathophysiology of this disease is not well understood as few cases have been documented. Hypothesized mechanisms include spinal cord lesions, dysfunction of inhibitory spinal interneurons, local structural neuron dysfunction, phrenic nerve irritation, lesions of the basal ganglia, or idiopathic etiologies.1 Given the unspecified pathophysiology and scant diagnostic tools available, treating this disease remains difficult. Case reports describe successful treatment with anti-convulsant medications, benzodiazepines, and first-generation antipsychotics, though research is limited.2The focus of this report was a 57-year-old female who presented with a history of constant, repetitive muscle spasms of her right upper abdomen present since undergoing an open cholecystectomy eight years prior. She failed multiple treatment regimens including pharmacologic, procedural, and physical therapy interventions. The patient’s disease left her in a state of extreme, daily discomfort and caused difficulty with eating more than one meal per day. Our combined anesthetic and surgical teams attempted a novel treatment with a combination of anesthetic agents and surgical re-incision and closure of the cholecystectomy site.The aim of this case study is to document this approach to treatment and its outcomes. The combined efforts of our anesthetic and surgical teams allowed our patient to be observed in real time while receiving a series of multi-modal treatments, culminating with re-incision and closure of the prior surgical site. Through this, we seek to provide new information to existing literature and improve the ability of other clinicians to effectively treat this disease.This study was exempted by the Colorado Multiple Institutional Review Board and written, signed consent was obtained from the patient. The following manuscript adheres to the applicable EQUATOR guidelines.