The grey wolf (Canis lupus L., 1758) exemplifies ecological resilience, surviving major climatic fluctuations since the Middle Pleistocene. Once the world’s most widely distributed mammal, its range has been drastically reduced by human-driven habitat loss, persecution, and competition for resources. Although globally listed as Least Concern by the IUCN, the omission of climate change as a threat raises critical questions about long-term resilience. This study investigates the dietary flexibility of European grey wolves across interglacials using dental microwear texture analysis (DMTA). We compare modern Polish wolves with fossils from two contrasting British interglacials: the Last Interglacial (MIS 5e) and penultimate interglacial (MIS 7a–c). By integrating palaeodietary data with palaeoenvironmental and palaeoclimatic evidence, we evaluate how past adaptive strategies may buffer wolves against future change. Results demonstrate deep-time dietary plasticity and recurrent behavioural shifts, suggesting that while the grey wolf is resilient, future warming winters may significantly reshape wolf diets in the mid-latitudes.