AbstractOsseous metaplasia (OM), defined as the formation of mature bone in non-osseous tissue, is a rare finding in colorectal adenocarcinoma, with a reported incidence of 0.15–0.4% and only one previously documented case from Ethiopia. We report a 54-year-old Ethiopian man with known colonic adenocarcinoma who presented with worsening fatigue, syncope, and vomiting over five days, along with a palpable right lower quadrant abdominal mass. Contrast-enhanced CT revealed circumferential asymmetric thickening of the cecum and ascending colon with small hyperdense calcified foci. Intraoperative findings showed a perforated cecal mass with minimal peritoneal contamination. Histopathologic examination demonstrated invasive adenocarcinoma with irregular glands and pleomorphic cells infiltrating the stroma, accompanied by benign trabecular bone formation with osteoblastic rimming, confirming osseous metaplasia. Although imaging may raise suspicion through the presence of calcifications, histopathology is required for definitive diagnosis. This case represents the first report of colonic adenocarcinoma with osseous metaplasia presenting with tumor perforation and emphasizes the importance of clinicoradiologic-pathologic correlation.Keywords : Adenocarcinoma; colon; osseous metaplasia; perforation; case report

AbstractUterine lipoleiomyoma is a rare subtype of leiomyoma composed of bundles of smooth muscle and fat. The majority of cases tend to be small and are usually diagnosed incidentally in obese postmenopausal women. Hereby we presented a large uterine lipoleiomyoma in a premenopausal woman presented with abnormal uterine bleeding. This case report highlights clinicoradiopathologic features of uterine lipoleiomyoma and briefly reviews the existing literature.