AbstractPancreatic hemangioma is an extremely rare benign tumor occurring in the pancreas. Preoperative diagnosis is challenging due to its lack of specificity on clinical manifestations and imaging examinations. Pancreatic lesion was found on physical examination in a 54-year-old woman who had no symptoms of abdominal discomfort. Computed tomography (CT) revealed a round, well-defined, and low-density nodule in the head of the pancreas with multilocular or honeycomb shape, with mild-moderate enhancement of its internal septum and no enhancement of the cystic component. Magnetic resonance imaging (MRI) showed an abnormal signal nodule in the head of the pancreas, with isointensity and hypointensity on T1-weighted images and inhomogeneous hyperintensity on T2-weighted images. The isointensity on diffusion weighted imaging (DWI) and high apparent diffusion coefficient (ADC) values suggested no significant diffusion restriction. In addition, the main pancreatic duct was not dilated and does not communicate with the lesion. Clinical consideration of pancreatic serous cystadenoma was highly probable. However, pancreatic hemangioma was confirmed postoperatively.