Background:Contrast-induced nephropathy is a common complication after cardiac interventional procedures. Methods: Our study assessed the application of risk score of Mehran, National Cardiovascular Data Registry-Acute Kidney Injury (NCDR) and 3-variable (AGEF score) based on age, left ventricular ejection fraction, and estimated glomerular filtration rate for contrast-induced nephropathy following Percutaneous Coronary Intervention in Chinese population. Discrimination of risk models was evaluated via the area under the receiver operating curve (AUC), while calibration of risk models was assessed by the goodness of fit test. Results: Discrimination of 3 risk models improved a lot with the definition of contrast-induced nephropathy that was recommend by Kidney Disease: Improving Global Outcome (KDIGO) than with the definition of contrast-induced nephropathy that was recommend by Contrast Media Safety Committee, European Society of Urogenital Radiology (ESUR CMSC). Mehran model and AGEF model exhibited good calibration. However, NCDR model obtained Hosmer-Lemeshow p value of 0.024 (contrast-induced nephropathy defined by ESUR CMSC) and Hosmer-Lemeshow p value of 0.118 (contrast-induced nephropathy defined by KDIGO). Conclusion: Mehran model, AGEF model and NCDR model showed favourable performance in contemporary Chinese interventional cardiology when the contrast-induced nephropathy definition was recommend by KDIGO.