INTRODUCTION: Systemic Lupus Erythematosus (SLE) is an autoimmune disorder that has variable severity, and can present with single or multisystem involvement but carries significant morbidity and mortality.Genetic and environmental factors disrupt immunological tolerance to self-antigens, leading to pathogenic autoantibodies that mediate tissue damage(1).The cases of SLE, just like any other autoimmune condition, are reported more among young females. Global SLE epidemiology in 2021 (2)revealed a marked increase in disease burden, with reported incidence ranging from 1.5 (3) to 11.0 (4) per 100,000 person years, and prevalence ranging from 13.0(5) to 7713.5 per 100000 individuals.One of the rare complications of SLE is the pseudo-pseudo megs syndrome, a combination of a triad of clinical conditions like Pleural effusion, Abdominal Ascites, and raised level of serum CA-125 unrelated to any gynecological malignancy, Tuberculosis, or other neoplastic condition(6).We describe a case of pseudo-pseudo Meigs syndrome in this case report. The objective of this study is to emphasize that early identification of this condition, followed by prompt treatment, can help reduce SLE-related morbidity and mortality.
