Results and Conclusion
Several new, functionalized IMPs (n=7) were synthesized and represent stable precursors for CO2 fixation. IMP-derived 11C-isocyanates successfully afforded structurally diverse radiolabeled ureas, (thio)carbamates and amides in one pot transformations, with moderate to high radiochemical yields (n=10, 7-99% d.c.). To confirm method’s applicability, automated production of radiopharmaceuticals will be performed.