Conventional pretreatment processes have been in commercial use for over 100 years and are relatively expensive to build and expensive to operate. These processes have evolved from low-volume edible oil refining with meaningfully different product requirements and are not well suited to petro-scale, high volume fuel production. This research explores the feasibility of a high temperature, selective hydrolysis, liquid-liquid extraction process as a more suitable alternative that offers lower capital cost, higher yield, lower variable cost, increased feedstock flexibility and streamlined operations. A series of benchtop batch reactions was performed to explore the design space as defined by reaction conditions such as temperature and residence time. Additionally, feedstock selection, water content, and catalyst were also varied in these benchtop trials. Upon discovering a range of conditions and reaction constituents that provided favorable results, a fully continuous pilot system was constructed to further explore the concept feasibility in a more commercially relevant environment. Starting feedstocks and pretreated samples were analyzed via ICP-OES with the target of achieving less than 2 ppm phosphorus and less than 5 ppm total metals in treated samples. This target was exceeded with a wide variety of feedstocks in the continuous pilot system. This research demonstrates the feasibility of a selective hydrolysis, liquid-liquid extraction process as a successful approach to feedstock pretreatment applicable to renewable fuel production. The process is also well suited for the purification of edible vegetable oils and industrial fats. This approach eliminates the complications and yield loss associated with centrifuges and sorbent powders while providing hardware that is more familiar to the fuel industry and better suited to high-volume oil processing.