Understanding the intricate ecological implications of species coexistence through trophic network analysis is crucial for biodiversity studies and for deciphering the environmental drivers of ecosystem dynamics. This study examines, in detail, the complexity, structure, and potential responses of the Strait of Magellan’s trophic network to both environmental and anthropogenic disturbances. Based on an extensive dataset of prey-predator interactions, we characterized the network’s topology and its theoretical resilience using a complex network methodology, analyzing the system at both the network-wide (holistic) and species-specific (reductionist) levels. Our analysis of 140 trophic species and 438 interactions reveals a network with low connectivity (0.022) and an asymmetrical distribution of links, where a few species disproportionately perform most interactions. The network exhibits a ”small-world” architecture, with high clustering and short path lengths, suggesting a rapid propagation of local disturbances. A significant proportion (over 50%) of species are omnivorous, a trait likely contributing to ecosystem stability amidst fluctuating prey availability. Key taxa – polychaetes, Fuegian sprat (Sprattus fuegensis) “sardina”, squat lobster (Grimothea gregaria) “langostino”, and Patagonian blenny (Eleginops maclovinus) “róbalo” – emerge as central conduits for matter and energy flow, effectively linking benthic and pelagic primary productivity to higher trophic levels and significantly underpinning ecosystem function. While the network shows potential robustness to general fluctuations, its concentrated interaction structure makes it vulnerable to the loss or migration of these pivotal species. These findings highlight the importance of understanding trophic relationships to inform effective conservation and ecosystem management strategies in this sensitive Sub-Antarctic marine region. This study provides a foundational understanding of the Strait of Magellan’s marine trophic architecture.