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Seher Kılıç
Seher Kılıç

Public Documents 1
Titanium-Induced Hypersensitivity Reaction in Implantable Cardioverter/Defibrillator:...
Seher Kılıç
Emir Baskovski

Seher Kılıç

and 3 more

April 26, 2025
A 47-year-old male presented to our clinic with heart failure with reduced ejection fraction. The patient was admitted, and an implantable cardioverter defibrillator (ICD) was implanted for primary prophylaxis. During the period following his discharge, the patient was readmitted due to pacemaker pocket infection. Despite the generators and ICD system being reimplanted on each hospitalization, the symptoms recurred. ICD generator was made of titanium alloy and a serial metal patch test was found to be positive for titanium oxalate hydrate. The ICD system was removed and re-implanted upon coating the generator with polytetrafluoroethylene (PTFE) sheets. There was no recurrence of pain or swelling around the generator pocket following implantation. Herein, we report our experience with the use of PTFE sheet coating to avoid contact sensitivity to pacemaker material.

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