Objective: We tried to examine the relationships between within-strategy emotion regulation tactics and symptoms of depression and anxiety in adolescents by conducting five meta-analyses. The examined tactics were emotional and situational acceptance, behavioral and cognitive distraction, non-judging and non-reactive mindfulness, behavioral and cognitive problem solving, and positive and relativizing reappraisal. The main question of our endeavor was whether the magnitudes of effect sizes differ between sibling tactics albeit being subtypes of the same emotion regulation strategy. Method: Scientific databases were searched to identify articles with adolescent samples (mean age 10 to 19 years; age range 8 to 21) in which bivariate correlations for at least one relationship of interest were reported. Results: We analyzed a total of 91 articles (92 studies) with 343 effect sizes and found differences in effect size magnitudes across all tactic siblings. The effect sizes ranged from -.46 to .01. Post-hoc analyses revealed that many effect size differences between sibling tactics depend on the particular emotion regulation questionnaire involved. Conclusion: Overall, the results imply the potential clinical importance for a context-dependent selection of emotion regulation tactics above and beyond strategies, and the need for a general tactic flexibility.