\fancypagestyle firstpage\fancyhf \lhead \chead \rhead \cfoot فروردین ماه ۱۴۰۴ Searching for low-cost sodium cathode materials with high theoretical capacity remains a key challenge in supporting the expansion of 5G base stations and alleviating the shortage of lithium resource. Among various candidates, manganese-based layered transition metal oxides have emerged as promising sodium-ion battery cathodes due to their high redox potential and theoretical capacity. However, their commercial application is hindered by poor structural stability and irreversible phase transitions. In this study, a high-entropy structured P2-Na0.47[Na0.2Mn0.54Ni0.13FexCuyCo0.13-x-y]O2 cathode material was synthesized via co-precipitation method, guided by density functional theory (DFT) calculations and entropy analysis. The relationship between elemental composition and electrochemical performance was systematically investigated. The action mechanism of Fe, Co co-doping on enhancing electrochemical property was explored from aspects of reaction energy and phase transition during charge-discharge process. Thanks to the key role of high entropy crystal structure, Na0.47[Na0.2Mn0.54Ni0.13Fe0.03Cu0.05Co0.05]O2 (NNMFCCO-5) delivers a high specific capacity of 123 mAh·g-1 at 1C and outstanding capacity retention of 89% after 100 cycles. Moreover, it also demonstrates excellent cycling stability in a full cell paired with hard carbon, maintaining over 90% capacity retention after 100 cycles at 1C. These findings provide both experimental and theoretical foundations for advancing the commercialization of P2-type manganese-based sodium cathode materials.