As a third-generation photovoltaic technology, perovskite solar cells (PSCs) have achieved record-breaking power conversion efficiencies (PCEs >26%) alongside industrial-grade operational stability, yet their commercialization hinges on resolving scale-up bottlenecks in monolithic module (PSM) fabrication. This study pioneers a data envelopment analysis (DEA) framework to evaluate 12 industrial PSM designs by quantifying manufacturing inputs (material costs, process steps) against performance outputs (PCE, degradation resistance). Results identify Pareto-optimal candidates (DMUs with CTE=1) that simultaneously achieve <5¢ W -1 production costs and roll-to-roll process compatibility, directly aligning with U.S. DOE’s photovoltaic cost roadmaps. By bridging materials innovation and high-throughput manufacturing metrics, this work establishes actionable guidelines to accelerate GW-year -1 deployment of PSMs while maintaining stoichiometric adaptability.