Objective : To compare Efficacy, Safety and Outcome of 25 ug sublingual misoprostol and 25 ug vaginal misoprostol administered for labour induction at term . Design : Observational Analysis of Retrospective study design . Settings : Dr M.K.Shah medical college and research institute, chandkheda Ahmedabad . Sample : A total of 200 Antenatal women at term with indication for labour induction. Methods: This retrospective observational study analyzed the records of 200 antenatal patients beyond 37 weeks. It included patients who received induction of labor through sublingual versus vaginal misoprostol. The data collection process involved a thorough examination of the case record form, capturing essential details such as patients’ age, parity, clinical presentations, examination findings, and results from clinical assessments and ultrasonography. Additionally, it included pre-induction CTG readings, Bishop scores, the method of administering tablet misoprostol, the quantity of tablets utilized, modes of delivery, fetal and maternal outcomes, any complications encountered, and NICU admissions. Main Outcome measure : The number of women delivering vaginally within 24 hours of induction labour . Results: The findings reveal that the most prevalent indication for labor was hypertensive disorder. The maximum dosage of misoprostol administered for induction, along with the amount of Oxytocin needed for augmentation, was two. Conclusion: The research findings indicate that vaginal misoprostol and sublingual misoprostol demonstrate comparable safety and efficacy as methods for labor induction.