Background: Borderline Personality Disorder (BPD) is a severe mental health condition characterized by emotional instability, impulsivity, and interpersonal difficulties, often emerging during adolescence. Early identification and intervention targeting traits such as emotional dysregulation and impulsivity may prevent progression to BPD. However, the evidence supporting prevention through early intervention remains limited. Objective: This systematic review examines whether BPD can be prevented when traits are identified during adolescence. It explores the prevalence of BPD traits, evaluates early interventions, and investigates familial and social factors shaping outcomes. Methods: A search of databases—PubMed, MEDLINE, EMBASE, PsycINFO, and Cochrane Central Register of Controlled Trials—identified 20 studies published between 2015 and 2024. The studies included adolescents aged 12–18 with BPD traits, interventions aimed at modifying these traits, and outcomes related to emotional and interpersonal functioning. Study designs ranged from randomized controlled trials to cohort studies and meta-analyses. Results: Approximately 10–15% of adolescents display BPD traits, emotional dysregulation, and impulsivity. Environmental factors, such as trauma and family dysfunction, exacerbate risk. Dialectical Behavior Therapy for Adolescents (DBT-A) and Mentalization-Based Therapy (MBT) were helpful. DBT-A cut self-harm by 45%, and MBT increased social skills by 38%. School-based social-emotional learning (SEL) programs enhanced emotional resilience and peer relationships. Long-term follow-ups indicated sustained benefits, particularly for DBT-A and family-based interventions, which reduced familial conflict by 50% and strengthened family bonds. Conclusion: Early intervention targeting BPD traits in adolescents reduces symptom severity, prevents progression, and integrates family and school support. Future research should focus on long-term studies, cultural adaptations, and underserved populations.