Culex mosquitoes are significant vectors of arboviruses and other pathogens. They exhibit diverse feeding patterns influenced by host availability, habitat type, or seasonality. In order to give insights across global, spatial, and seasonal dimensions of their feeding patterns we performed a meta-analysis integrating 144 studies. Our results revealed that Culex mosquitoes predominantly feed on wild birds, with proportions exceeding 50% across species and habitats. Notably, Culex quinquefasciatus displayed a great plasticity, including significant feeding on fowls (26%) and humans (16%). Habitat type influenced feeding preferences, with urban environments showing increased feeding on humans (11.8%) compared to non-urban (6.3%) and peri-urban (10.32%) settings. Seasonal variations indicated higher mammalian feeding in autumn (e.g., humans 9%) compared to summer (4.94%). These findings highlight the importance of understanding Culex host interactions across diverse landscapes to mitigate mosquito-borne disease transmission effectively.