Total N = 292 Normal Growth = 213/292 (73%) FGR/SGA = 79/292 (27%) Fetal Growth Restriction (FGR) / Small for Gestational Age (SGA) Compromised Fetal Growth Normal Fetal Growth OR (CI95%) p value
Early Onset FGR < 32w EFW < 3% N=36 Late Onset FGR > 32w EFW < 3% N=10 Early Onset SGA < 32w EFW 4-10% N=21 Late Onset SGA > 32w EFW 4-10% N=12 FGR/SGA N= 79 EFW 11-90% N=213
Placental Growth Factor (PlGF)
Low (≤5%) 27 75% 7 70% 12 57% 4 33% 50 63% 55 26% 4.9 (2.9-8.5) <0.0001*
Normal (≥10%) 9 25% 3 30% 9 43% 8 67% 29 37% 158 74%
US Findings
Abnormal Placental Morphology 22 61% 6 60% 14 67% 7 58% 49 62% 50 23% 5.3 (3.1-9.1) <0.0001*
Perinatal Outcomes
Preeclampsia at any Gestational Age 14 39% 4 40% 4 19% 5 42% 27 34% 56 26% 1.5 (0.84-2.52) 0.18*
Fetal Demise (IUFD) 4 11% 0 0% 1 5% 1 8% 6 7.6% 1 0.5% 12.5 (2.08-75.42) 0.001**
Preterm birth < 34 weeks 20 56% 3 30% 5 23% 1 8% 29 37% 27 13% 3.99 (2.12-7.22) <0.0001*
Birthweight < 3% 10 28% 2 20% 0 0% 1 8% 13 16.5% 4 2% 10.3 (3.28-29.46) <0.0001**
Admission to NICU 18 50% 8 80% 8 38% 3 25% 37 47% 40 19% 3.81 (2.15-6.52) <0.0001*
Placental Pathology
Confirmed Maternal/Fetal Vascular Malperfusion (MVM/FVM) 21 58% 5 50% 10 48% 4 33% 40 51% 27 13% 7.06 (3.92-12.62) <0.0001*