Table S3. Main characteristics of patients enrolled in included studies.
Table S4. Assessment of risk of bias in the included studies using RoB2 for RCTs studies.
Figure S1 . Flow-chart of trials included in the meta-analysis.
Figure S2 . Summary baseline of lipids and lipoproteins in PCSK9i compared to ANGPTL3i
Figure S3. Mean changes of lipid profile in PCSK9i compared to ANGPTL3i: A) TC; B) LDL-C Figure S4. Mean changes of lipid profile in PCSK9i compared to ANGPTL3i: A) HDL-C; B) TG
Figure S45 Mean change of lipoproteins in PCSK9i compared to ANGPTL3i: A) Lp (a); B) Apo B; C) Apo A
Figure S6. Mean change of LDL-C in PCSK9i compared to ANGPTL3i in different age: A) Adult; B) Children