Table of Abbreviations
AC Adenylate cyclase
AKT Protein kinase B
Asp Aspartic acid
CA Constitutive activity
Ca2+ Calcium
cAMP Cyclic adenosine monophosphate
CCL C-C chemokines
CCR C–C Chemokine receptor
CCR2 C-C chemokine receptor type 2
CCR5 C-C chemokine receptor type 5
COSMIC Catalogue of Somatic Mutations in Cancer
CXCR C-X-C chemokine receptor
CXCR1 C-X-C Motif Chemokine receptor 1
DAG Diacylglycerol
DRD1 Dopamine receptor D1
ECL Extracellular loop
ER Estrogen receptor
ERK Extracellular signal-regulated kinases
FDA Food and Drug administration
GEF Guanine nucleotide exchange factors
GNA11 G Protein Subunit Alpha 11
GNAQ G Protein Subunit Alpha Q
GNAS G protein Subunit Alpha S
GnRH Gonadotropin releasing factor hormone receptor
GOF Gain of function
GPCR G protein-coupled receptor
GRK G protein-coupled receptor kinase
GRMM1-8 Glutamate family of G protein-linked
ICL Intracellular loop
IP3 Inositol 1,4,5-trisphosphate
LHCG Lutropin receptor
LOF Loss of function
LPA Lysophosphatidic acid receptors
mAChR Muscarinic acetylcholine
MAPK Mitogen-activated protein kinase
MC1R Melanocortin 1 receptor
MC2R Melanocortin 2 receptor
PI3K Phosphoinositide 3-kinase
PIP2 Phosphatidylinositol 4,5-bisphosphate
PKA Protein Kinase A
PLC Phospholipase C
S1P Sphingosine-1-phosphate
SMO Smoothened receptors
SMO Smoothened receptor
SSTR Somatostatin receptors
TM Trans membrane α-helix
TSHR Thyroid-stimulating hormone receptor
VEGF Vascular endothelial growth factor
UCEC Uterine Corpus Endometrial Carcinoma
SKCM Skin Cutaneous Melanoma
LUAD Lung adenocarcinoma
COAD Colon adenocarcinoma
STAD Stomach adenocarcinoma