Aim To evaluate and summarize the evidence that cognitive behavioral therapy for insomnia improves sleep quality in patients with chronic insomnia and provide reference for clinical practice. Design The PIPOST model from the Center for Evidence-Based Nursing at Fudan University was used to retrieve evidence and integrate it through structured evidence-based questions. Methods Current literatures were systematically searched for the best evidence that cognitive behavioral therapy for insomnia improves sleep quality in patients with chronic insomniaLiterature types included clinical guidelines,best practice information sheets, expert consensuses, systematic reviews, evidence summaries and cohort studies. Data Sources UpToDate,BMJ Best Practice,Joanna Briggs Institute,Guidelines International Network,National Institute for Health and Care Excellence,Registered Nurses Association of Ontario,Scottish Intercollegiate Guidelines Network,the Cochrane Library, Embase,PubMed, Sinomed,Web of Science,DynaMed,MEDLINE, CNKI, WanFang database, Chinese Medical Journal Full-text Database,The search period was from build to December 10, 2024 Results A total of 28 papers were included,including 5 guidelines,3 expert consensus papers,12 systematic evaluations, and 8 Meta-analyses, and the overall quality of the included papers was high.Forty-one pieces of best evidence were summarized in terms of diagnostic criteria for sleep disorders,assessment conditions, timing of initiation of multicomponent cognitive behavioral therapy for sleep (CBT-I), treatment format,composition of components,assessment metrics,assessment tools, symptom improvement metrics, comparisons of implementers, and adverse effects. Conclusion The study summarizes the best evidence that CBT-I improves sleep quality in patients with chronic insomnia and recommends that clinical staff should fully assess the patient’s overall condition before implementing the therapy and develop a personalized CBT-I treatment plan for the patient based on their assessment.