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\begin{document}

\title{Current Biology Article Template ~ ~ ~\\}


\author[ ]{Josh Nicholson}

\affil[ ]{}
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\date{}

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\begin{abstract}
\subsection*{\texorpdfstring{General Research Article Organization and
Text Specifications\\
}{General Research Article Organization and Text Specifications }}\label{general-research-article-organization-and-text-specifications}

\emph{Current Biology~}research articles generally contain the following
sections in this order: Title, Authors, Affiliations, Contact
Information, Additional Title Page Footnotes, Summary, Introduction (for
Articles only), Results, Discussion, Experimental Procedures, Author
Contributions, Acknowledgments, References, Figure and Table Legends,
Figures and Tables, Graphical Abstract (optional, see below), and
Supplemental Information. The text (title through legends) should be
provided as one document, which may also contain the tables. Figures
should be provided
separately.~\href{http://www.cell.com/supplemental-information}{Supplemental
Information}~should also be provided separately.\\

Gene symbols should be italicized; protein products of the loci are not
italicized. Nonstandard abbreviations should be defined when first used
in the text. Use of abbreviations should be kept at a minimum.
Manuscript file types that we can accept for submission include Word,
RTF, and TXT. Required items differ for each article type and are
specified during the submission process.\\

Please note that the text should be double spaced and pages should be
numbered. Although summaries need to be entered as text files separate
from the body of the manuscript during the online submission process,
they should also be included within the manuscript file as usual.\\

\textbf{Manuscripts that do not conform to the format guidelines may be
returned to the authors for reformatting.}\\

\subsection*{\texorpdfstring{Preparation of Specific Sections\\
}{Preparation of Specific Sections }}\label{preparation-of-specific-sections}

\subsubsection*{\texorpdfstring{Title\\
}{Title }}\label{title}

Titles can occupy no more than three lines of type. Each line can
contain no more than 50 characters, including spaces. The title should
convey the conceptual significance of the paper to a broad readership.\\

\subsubsection*{\texorpdfstring{Authors/Affiliations\\
}{Authors/Affiliations }}\label{authorsaffiliations}

Author names should be spelled out rather than set in initials. Authors
should be footnoted to corresponding affiliations. Affiliations should
contain the following core information: department(s)/subunit(s);
institution; city, state/region, postal code; country.~Note: Please
check author names and affiliations carefully, as we cannot amend or
correct these sections after publication.\\

\subsubsection*{\texorpdfstring{Corresponding Author\\
}{Corresponding Author }}\label{corresponding-author}

The ``Correspondence'' line should include the e-mail address(es) of the
corresponding author(s). One corresponding author is preferred for
reasons stated in the Authorship section of Editorial Policies above.
But there is no mandatory limit on the number of corresponding authors
that may be listed.~Corresponding authors may also provide a Twitter
handle as a secondary means of contact. Please see the corresponding
author responsibilities noted above in the Editorial Policies.\\

\subsubsection*{\texorpdfstring{Lead Contact\\
}{Lead Contact }}\label{lead-contact}

Every author list must identify one corresponding author as a Lead
Contact, noted by a footnote in the manuscript. If there is only one
corresponding author, that author will be listed as the Lead Contact.
Please see the Lead Contact responsibilities noted above in the
Authorship section of the Editorial Policies.\\

\subsubsection*{\texorpdfstring{Additional Footnotes\\
}{Additional Footnotes }}\label{additional-footnotes}

Footnotes are only allowed on page 1 of the text (and in tables). They
may include a Lead Contact (mandatory) or a present address (optional),
or they may indicate co-first authorship (optional).~For more on
designations of author contributions, please see the ``Authorship''
section above, under Editorial Policies.\\

\subsubsection*{\texorpdfstring{Summary (for Articles)\\
}{Summary (for Articles) }}\label{summary-for-articles}

The Summary should not exceed 250 words, should contain no references,
and should be written as a single paragraph that summarizes the
background to the study, the key results, and the conclusions. It should
clearly convey the conceptual advance and significance of the work to a
broad readership.\\

\subsubsection*{\texorpdfstring{Summary (for Reports)\\
}{Summary (for Reports) }}\label{summary-for-reports}

The Summary should be written as a single paragraph that summarizes, in
no more than 250 words, the background to the work, the new results
being reported in the study, and the significance of these findings;
references should also be cited in this paragraph. Please note that, for
Reports, all essential background information should be included in the
summary, and the Results (or Results and Discussion) section should
begin immediately with a presentation of the new findings.\\

\subsubsection*{\texorpdfstring{Keywords\\
}{Keywords }}\label{keywords}

Authors are encouraged to include up to ten keywords that will be
associated with the article on Cell Press platforms and on PubMed. These
keywords should be listed in the manuscript after the Summary, separated
by commas.\\

\subsubsection*{\texorpdfstring{Highlights and eTOC Blurb\\
}{Highlights and eTOC Blurb }}\label{highlights-and-etoc-blurb}

Highlights are a short collection of bullet points that convey the core
findings of the article.~\emph{Specifications}: up to four bullet points
may be included; the length of an individual bullet point should not
exceed 85 characters (including spaces); only the core results of the
paper should be covered.\\

The eTOC blurb is a short summary of the main take-home message of the
paper and should describe the context and significance of the findings
for the broader readership. Please see the ``In Brief'' links in the
Table of Contents for examples.~\emph{Specifications}: This blurb should
be 350 characters or fewer; this blurb should be written in the third
person and refer to ``First Author et al.''\\

Both are required for all research papers and will be displayed online
with the article; however, they will not appear in print. On the EM page
where you are asked to upload your files, please choose ``Highlights and
eTOC Blurb'' and upload a single Word document containing both your
Highlights and the eTOC Blurb.\\

\subsubsection*{\texorpdfstring{Introduction (for Articles)\\
}{Introduction (for Articles) }}\label{introduction-for-articles}

The Introduction must be written from the standpoint of biologists
without special knowledge, must clearly state the background to the
research and its aims, and should end with a brief statement of what has
been achieved.\\

\subsubsection*{\texorpdfstring{Results (for Articles)\\
}{Results (for Articles) }}\label{results-for-articles}

This section should be divided into subsections with short informative
subheadings. Footnotes should not be used.\\

\subsubsection*{\texorpdfstring{Discussion (for Articles)\\
}{Discussion (for Articles) }}\label{discussion-for-articles}

The Discussion must clearly explain the main conclusions of the research
and give clear explanations of their importance and relevance, placing
them into a broader context. It should not be redundant with the Results
section. This section may contain subheadings and can in some cases be
combined with the Results section. A separate short Conclusions section
may also be included if useful.\\

\subsubsection*{\texorpdfstring{Results and Discussion (for Reports)\\
}{Results and Discussion (for Reports) }}\label{results-and-discussion-for-reports}

The Results and Discussion for Reports may be combined or kept separate
and may be broken into subsections with short informative subheadings.
The final paragraph should summarize the main findings of the research
and their implications. Footnotes should not be used.\\

\subsubsection*{\texorpdfstring{Experimental Procedures (for Articles)\\
}{Experimental Procedures (for Articles) }}\label{experimental-procedures-for-articles}

The Experimental Procedures should, at minimum, include enough detail to
allow the reader to understand the general experimental design and to be
able to assess the data presented in the figures.~This section should
also include a description of any statistical methods employed in the
study.~More detailed protocols and procedures needed for readers to
reproduce experiments should be included in the Supplemental
Experimental Procedures, but it is not appropriate to move the majority
of the Experimental Procedures to Supplemental Information in order to
shorten the text. Any supplemental tables that list materials used in
the study (oligonucleotides, strains, etc.) should be included within
the relevant section of the Supplemental Experimental Procedures; these
tables should have a title but should not be numbered. If your paper
contains Supplemental Experimental Procedures, please make sure that
they are referred to within the main Experimental Procedures so that it
is clear to the reader that additional details are available online.
Please see our
complete~\href{http://www.cell.com/supplemental-information}{Supplemental
Information~guidelines}~for more information.\\

\subsubsection*{\texorpdfstring{Experimental Procedures (for Reports)\\
}{Experimental Procedures (for Reports) }}\label{experimental-procedures-for-reports}

Experimental Procedures should be divided into subsections. A separate
section may not be necessary in a Report if methods can be described
concisely and adequately in the text and figure/table legends, but more
detailed protocols and procedures needed for readers to reproduce
experiments should be included in the Supplemental Experimental
Procedures.\\

\subsubsection*{\texorpdfstring{Author Contributions\\
}{Author Contributions }}\label{author-contributions}

For primary research papers, we ask you to include a dedicated Author
Contributions section preceding the Acknowledgments to give information
about individual author contributions to the work. Please keep this
section as concise as possible and use initials to indicate author
identity. All of the authors listed on the paper should be mentioned in
this section at least once. We are happy for you to use a traditional
format such as ``A.B. and C.D. conducted the experiments, E.F. designed
the experiments and wrote the paper\ldots{}'' but would also encourage
you to
use~\href{http://www.cell.com/pb/assets/raw/shared/guidelines/CRediT-taxonomy.pdf}{the
CRediT taxonomy}~instead.\\

\subsubsection*{\texorpdfstring{Acknowledgments\\
}{Acknowledgments }}\label{acknowledgments}

This section may acknowledge contributions from non-authors and/or list
funding sources, and it should include a statement of any conflicts of
interest.~Please check this section carefully, as we cannot allow
amendments or corrections after publication.\\

\subsubsection*{\texorpdfstring{References\\
}{References }}\label{references}

References must be cited by number consecutively in square brackets in
the text. Any references that occur only in the tables or figure legends
should be numbered according to where that table or figure is first
cited in the main text, in relation to the sequence of citation
numbering. (For example, if the last reference cited before the first
citation of Figure 1 was reference {[}15{]}, and the Figure 1 legend
contains a reference that is first cited in the Figure 1 legend, that
reference should be numbered as {[}16{]}, and the next reference cited
in the main text would be {[}17{]}.) References should include only
articles that are published or in press. For references to in press
articles, please confirm with the cited journal that the article is in
fact accepted and in press and include a DOI number and online
publication date. Unpublished data, submitted manuscripts, abstracts,
and personal communications should be cited within the text only.
Personal communication should be documented by a letter of permission.
Submitted articles should be cited as unpublished data, data not shown,
or personal communication. Journal abbreviations should follow Index
Medicus/Medline. Up to ten authors, followed by et al. if there are more
than ten authors, should be listed. References should be
in~\emph{Current Biology}~numbered style, examples of which are included
below:\\

\textbf{Article in a periodical:}\\

1. Holmes, S., and Watson, J. (1993). Identification of the function of
the~\emph{moriarty}~gene product. Curr. Biol.~\emph{3}, 121--129.\\

\textbf{Article in a book:}\\

2. Holmes, S., and Watson, J. (1991). Identification of the function of
the~\emph{moriarty}~gene product. In Biological Mysteries Solved, A.C.
Doyle, ed. (London: Science Press), pp. 56--62.\\

\textbf{An entire book:}\\

3. Doyle, A.C. (1991). Biological Mysteries Solved, Second Edition
(London: Science Press).\\

\subsubsection*{\texorpdfstring{Figure Legends\\
}{Figure Legends }}\label{figure-legends}

Legends should be included in the submitted manuscript as a separate
section. Each figure legend should have a brief title that describes the
entire figure without citing specific panels, followed by a description
of each panel. For any figures presenting pooled data, the measures
should be defined in the figure legends (for example, ``Data are
represented as mean \selectlanguage{ngerman}± SEM.''). Each legend should refer to any
supporting items in the Supplemental Information (e.g., ``See also
Figure S1.'').\\

\subsubsection*{\texorpdfstring{Tables\\
}{Tables }}\label{tables}

When creating a table, please use the Microsoft Word Table function.
Tables should include a title, and footnotes and/or legend should be
concise. Include tables in the submitted manuscript as a separate
section. Tables not created with the Microsoft Word table function will
need to be revised by the author.\\

When creating tables, please adhere to the following guidelines:\\

\begin{itemize}
\tightlist
\item
  Do not submit tables in Excel or PDF format. Do not place an Excel
  table in a Word document.\\
  \hspace*{0.333em}\\
\item
  Format tables with Word's Table function; do not use tabs or spaces to
  create a table.\\
  \hspace*{0.333em}\\
\item
  Do not use line breaks or spaces to separate data within a cell. Use
  separate cells for all discrete data elements within a table.\\
  \hspace*{0.333em}\\
\item
  Number tables as Table 1, Table 2, Table 3, etc., rather than as Table
  1a, Table 1b, Table 1c, etc.\\
  \hspace*{0.333em}\\
\item
  If bold or italic font is used within a table to indicate some feature
  of the data, please give an explanation of its usage in the legend.\\
  \hspace*{0.333em}\\
\item
  All abbreviations within a table must be defined in the table legend
  or footnotes.\\
  \hspace*{0.333em}\\
\item
  Footnotes should be listed with superscript lowercase letters,
  beginning with ``a.'' Footnotes may not be listed with numbers or
  symbols.\\
\end{itemize}

\subsubsection*{\texorpdfstring{~\\
}{~ }}\label{section}

\subsubsection*{\texorpdfstring{Supplemental Information\\
}{Supplemental Information }}\label{supplemental-information}

In general, Supplemental Information is limited to data and other
materials that directly support the main conclusions of a paper but
cannot be included in the main paper for reasons such as space or file
format restrictions.~Supplemental Information~should not be~used to
present data that are preliminary or that conceptually go beyond the
main point of the paper.\\

Before submitting your supplemental materials, please refer to our
complete instructions in
the~\href{http://www.cell.com/supplemental-information}{Supplemental
Information guidelines}. This page also contains information on
submitting movie and other multimedia files.\\

\subsection*{\texorpdfstring{Figures and Graphical Abstracts\\
}{Figures and Graphical Abstracts }}\label{figures-and-graphical-abstracts}

Digital figure files submitted
through~\href{http://www.editorialmanager.com/current-biology/?__hstc=25856994.aadc40902d970d22758a35bbc04a125f.1464096900346.1469466741155.1469473521184.12\&__hssc=25856994.1.1469473521184\&__hsfp=13480855}{Editorial
Manager}~must conform to
our~\href{http://www.cell.com/figureguidelines}{digital figure
guidelines}~or authors will be asked to revise them.\\

If you have any questions about digital files, please contact Jackie
Doyle, Managing Editor of~\emph{Current Biology},
at\href{mailto:jdoyle@cell.com}{\nolinkurl{jdoyle@cell.com}}.~\\

\subsubsection*{\texorpdfstring{Graphical Abstract\\
}{Graphical Abstract }}\label{graphical-abstract}

A graphical abstract should allow readers to quickly gain an
understanding of the main take-home message of the paper and is intended
to encourage browsing, promote interdisciplinary scholarship, and help
readers identify more quickly which papers are most relevant to their
research interests. Examples of this feature can be seen in the online
version of articles published in~\emph{Cell}~from January 2010 onwards.
Graphical abstracts may be submitted at any stage up to acceptance for
publication (it is not necessary to provide a graphical abstract for a
new submission). Graphical abstracts can be uploaded
in~\href{http://www.editorialmanager.com/current-biology/?__hstc=25856994.aadc40902d970d22758a35bbc04a125f.1464096900346.1469466741155.1469473521184.12\&__hssc=25856994.1.1469473521184\&__hsfp=13480855}{Editorial
Manager}~by selecting ``Graphical Abstract'' when uploading files.~Refer
to our~\href{http://www.cell.com/figureguidelines}{digital figure
guidelines}~for graphical abstract preparation details.\\%
\end{abstract}%





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