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\begin{document}

\title{Science Article Template\\}


 \author{The Authorea Team}


\date{}

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\textbf{Science} \textbf{Manuscript Template}

\textbf{General Instructions on using this template and submitting a
manuscript to Science:} Thank you for preparing a manuscript for
submission to Science. Using this template, or following the guidelines
below, will help us in processing your paper. Our goal is to be able to
identify each section of your manuscript so that we can accurately
record the title, authors, abstract, etc. and also be able to enrich it
by including reference links and an accurate layout.

Please use the actual template, which starts on page 2. delete the text
on this cover page.

You can submit your paper at www.submit2science.org

Additional instructions are available at
http://www.sciencemag.org/site/feature/contribinfo/index.xhtml

If you are using LaTeX , please convert your paper into a Word or RTF
file if possible. If this is not possible, please use our LaTeX template
and upload a PDF version of your paper. Some conversion approaches are
available here: http://www.tug.org/utilities/texconv/textopc.html

So that we can identify the parts of your paper, and even if you do not
use our template, please begin each section with the specific key words
listed below, some of which are followed by a colon. Please do not use
paragraph breaks in the title, author list, or abstract.

\textbf{Title:}

\textbf{Authors:}

\textbf{Affiliations:}

\textbf{One Sentence Summary:}

\textbf{Abstract:}

\textbf{Main Text:}

\textbf{References and Notes} (followed by a numbered list)

\textbf{Acknowledgements:}

\textbf{Fig. \#:} (Begin each figure caption with a label,
``\textbf{Fig. 1}.'' for example, as a new paragraph.).

\textbf{Table \#:} (Begin each table caption with a label
``\textbf{Table 1.''}, etc.) as a new paragraph.

\textbf{Supplementary Materials:} a list of the supplementary materials,
followed by the actual text of the Supplementary Materials.

Several of these headings are optional, for example, not all papers will
include a one-sentence summary, figures or tables, or supplementary
material.

Please use the .docx format if possible (all version after Word 2007).

More specific formatting instructions are provided in the actual
template, which follows.

Title: How to Format a Science Paper (replace with your real title)

\textbf{Authors:} The author list should be one single paragraph (no
breaks). Authors should be listed by first name or initial followed by
last name and separated by commas. Use superscript numbers to link
affiliations, and symbols *+++ for author notes. For example, X. Jones1*,
P. Smith1,2

\textbf{Affiliations:}

1Affiliations should be preceded by superscript numbers corresponding to
the author list, and each affiliation should end with a period.

2Each affiliation should be a separate paragraph.

3You can include group authors, but please include a list of the actual
authors in the Supplementary Materials.

*Correspondence to: include the email addresses of the corresponding
author(s). Please use the asterisk (*) symbol for the corresponding
author information.

+Additional author notes should be indicated with symbols (for example,
for current addresses).

\textbf{Abstract} : The abstract should be about 100-150 words, and
organized in this structure: An opening sentence that sets the question
that you address and is comprehensible to the general reader, background
content specific to this study, results, and a concluding sentence. It
should be one paragraph only.

\textbf{One Sentence Summary:} A brief summary of the main result of
your paper, without excessive jargon and less than 150 characters.

\textbf{Main Text:} In general, this should include a brief (1-2
paragraph) introduction, followed by a statement of the specific scope
of the study, followed by results and then interpretations. Please avoid
statements of future work or claims of priority, and avoid repeating the
conclusions at the end. All of the Figures and Tables should be cited in
order, including those in the supporting online material (which should
be cited as, for example, figure S1, and table S1). You can include page
breaks if you would like to place the figures within the text.

\textbf{Subheads} . These can be included in Research Articles or
Reviews and should be brief.

References should be cited in parentheses with an italic number (1).
Multiple reference citations are separated by commas (2, 3) or if a
series, dashes (4-6). References are cited in order by where they first
are called out, through the text, then the notes, captions, then through
the supplementary material.

Equations can be included. We do not recommend using the native Word
2007, 2008, 2010 or 2011 equation editor. This can in some cases produce
less reliable MathML, the online markup language we use, which may
result in display errors. Instead, use the legacy equation editor in
word (Insert menu; select insert object; select word equation) or use
Mathtype (recommended). If you enter equations in simple LaTeX, check
that they will convert accurately (Word 2007 and higher can convert
simple LaTeX equations).

References and Notes:

\begin{enumerate}
\tightlist
\item
  There is only one reference list spanning the text, figure captions
  and supplementary materials. Do not include a second reference list in
  the supplementary materials section. Reference only cited in the
  supplementary materials section are not counted toward length
  guidelines.
\item
  Each reference should be on a separate line ending in a period. For a
  style guide, see www.sciencemag.org/about/authors/prep/res/refs.xhtml
  .
\item
  You can include titles in references and full page ranges. Titles are
  not counted toward length guidelines
\item
  Please include the above heading ``References and Notes:''
\item
  You can use a numbered list in Word.
\item
  Each references should have a separate number.
\item
  Please do not mix in references with explanatory notes.
\end{enumerate}

\textbf{Acknowledgments:} The acknowledgments should include a statement
about where the data reported in the paper are presented, archived, or
available (for example, in the Supplementary Materials or in a community
archive). If in an archive, include the accession number or a
placeholder for it. Please also include relevant funding information
such as grant numbers and funding agencies. You can also include a
statement of author contributions here or in the Supplementary
Materials.

The acknowledgements can be multiple paragraphs. Acknowledgments follow
the references and notes but are not numbered.

\textbf{Fig. 1} . The figure caption should begin with an overall
descriptive statement of the figure followed by additional text. They
should be immediately after each figure. Figure parts are indicated with
capital letters (\textbf{A}). If you prefer, you can place both the
actual figures and captions logically through the text near where they
are cited rather than at the end of the file (but not both). If a
paragraph in the main text begins with the name of a figure, write out
``Figure'' in full (e.g., \textless{}para\textgreater{}``Figure 1
shows\ldots{}.'')

\textbf{Fig. 2.} You can place graphics above each equation as part of
this file.

\textbf{Table 1.} Start this caption with a short description of your
table. Format tables using the Word Table commands and structures. Do
not create tables using spaces or tabs characters.

Supplementary Materials:

Materials and Methods

Figures S1-S\#

Tables S1-S\#

Movies S1-S\#

Audio Files S1-S\#

External Databases S1-S\#

References (\#\#-\#\#)

Supplementary Materials:

This section includes the actual text of the Supplementary Materials,
which can include any or all of the preceding items, and figure captions
and tables that can easily be incorporated into one supplementary
material file. Please edit the list above as appropriate and include it
at the end of your main paper. If there are additional files that cannot
be easily accommodates (e.g., movies or large tables), please include
captions here.

\textbf{Materials and Methods:} Can include the Materials and Methods
here. Additional references should be cited here and included in the
main reference list.

\textbf{Any Additional Author notes:} For example, author contributions
or a list of group authors.

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