Objective: To assess whether transvaginal infiltration with anaesthetic only is non-inferior compared to anaesthetic plus corticosteroid for the treatment of myofascial pelvic pain. Design: Randomised, double-blind, parallel-group (1:1) clinical trial. Setting: Department of Obstetrics and Gynaecology, Hospital Universitario “Príncipe de Asturias” from December 2017 to June 2023. Population: Women presenting myofascial perineal pain ≥4 on the visual analogue scale (VAS) 2 months after delivery, with instrumental delivery or prolonged second stage (>3 hours) or foetal weight >4000 g. Methods: Patients were randomised into two groups to receive levobupivacaine 5 mg/mL, or levobupivacaine 5 mg/mL plus betamethasone 3 mg/mL. For each trigger point detected, a transvaginal infiltration was performed using the corresponding treatment. Patients were followed up to 6 months. Main Outcome: Primary endpoint was change in the VAS score from baseline at 6 months. Results: A total of 114 women were enrolled, with 57 randomly assigned to each group. Median (IQR) VAS 2 weeks after infiltration decreased by a similar magnitude: median (IQR) 2 (1-3) in the levobupivacaine group and 2 (1-4) in the levobupivacaine + betamethasone group ( p-value = 0.33). Same trend was observed at 6 months: median (IQR) 1 (1-4) in the levobupivacaine group and 1 (1-2) in the levobupivacaine + betamethasone group ( p-value = 0.85). Conclusions: This study provides evidence that the use of anaesthetic only infiltration is non-inferior compared to anaesthetic plus corticosteroid for the treatment of myofascial perineal pain. Funding: Trial was supported by a grant from the “Príncipe de Asturias” Hospital Foundation. Keywords: infiltration, myofascial pelvic pain, postpartum