Introduction
Scleredema is a rare connective tissue disease of unknown pathogenesis, and may be associated with autoimmune phenomena or allergic responses [1]. It is characterized by the progressive development of skin thickening and tightness on the neck and upper part of the body [2]. The prognosis varies according to the etiology and therapeutic options. In addition to skin lesions, scleredema involves endocrine/metabolic disorders, cardiovascular disorders, hematologic disorders, gastrointestinal disorders, and other systemic dysfunctions [3]. In particular, previous cases reported that scleredema associated cardiomyopathy, and its pathogenesis may be driven by the lymphocyte response [4,5]. It is still under investigation in clinical practice whether scleredema patients develop cardiomyopathy. We report a case of scleredema in a 32‑year‑old male with cardiomyopathy. The purpose of this case report is to raise awareness of scleredema-associated cardiomyopathy and contribute further insight to explore and establish the foundation for the cause of this uncommon cardiomyopathy.