Lung cancer is worldwide the leading non-skin cancer-related cause of death and the second most diagnosed malignancy. Currently, many immunohistochemistry essays can provide precise end of line histological diagnosis, improving overall survival through efficient individualized treatment schemes. There seems to be a radiological correlation between the two basic histological tumor subtypes (adenocarcinoma and squamous cells carcinoma) and nodule site presentation in chest imaging, and although this is considered in many radiology manuals, the reasons for such presentation patterns are seldom investigated. We intend to present hypothesis and reasonable explanations for the practical consensus widely acknowledged in the manuals, considering cell types in the lung topography and histological markers in carcinogenesis which should be able to clarify wether the imaging pattern is statistically true and why certain tumor types prefer their usual sites, being adenocarcinomas preferably peripheral and squamous cell carcinoma central.

Objective: To estimate endometritis rates across delivery methods and analyze associations with maternal and delivery variables in Brazil. Design: Observational, retrospective cohort study. Setting: Maternity Hilda Brandão, Santa Casa de Belo Horizonte Hospital, Minas Gerais, Brazil. Population: 35,744 pregnant women admitted for delivery from January 2013 to December 2022. Methods: Analysis of delivery outcomes across vaginal births (62.1%), forceps deliveries (4%), and cesarean sections (33.9%). Multivariate logistic regression was used to identify factors associated with endometritis. Main Outcome Measures: Endometritis rates by delivery method and associated risk factors. Results: Overall endometritis rate was 0.6% (224/35,744). Cesarean sections showed 1.34 times higher risk of endometritis compared to vaginal births (p=0.032), with significantly higher risk during labored cesareans (OR=2.297, p<0.001). No significant difference was found between induced and spontaneous labor (OR=1.07, p=0.680). Preterm birth and primiparity were identified as risk factors. Conclusions: Cesarean delivery, particularly during labor, significantly increases endometritis risk. Maternal comorbidities and previous cesareans showed no significant association with endometritis.