Statistical analysis
The data from three replicates per experiment are summarized as mean ±
SD. The statistical analysis involved one-way ANOVA, followed by the
Student-Newman-Keuls’ test for multiple comparisons within treatment
groups or Student’s t test for comparisons between two groups.
ROC curves and the corresponding area under the curve (AUC) were
generated via the R package ”pROC” to assess the diagnostic value of
TP53BP2. A significance threshold of P <0.05 was applied.