Acknowledgments
This work was supported by the grants from the National Natural Science Foundation of China (82370293, 82270492,82171682, 81900273 ,82371598); Key Research and Development Projects in Ningxia Province (2023BEG02074, 2022BFH02013, 2022BEG02054, 2021BEG02028); Major Scientific Research Project for High level Health Talents in Hunan Province (R2023120). The Open competition mechanism to select the best candidates for key research projects of Ningxia medical university (Nos.XJKF240301 and XJKF240304); The Natural Science Foundation of Ningxia Hui Autonomous Region (Nos. 2023AAC005035).