Title page:Conservative Management of Thrombotic Microangiopathy in a Renal Transplant Recipient: The Importance of Early RecognitionAuthors:Ahmad S. Matarneh (1), Sundus Sardar (1), Abdel-rauof Akkari (1), Pankhuri Mohan (2) Naman Trivedi (1), Gurwant Kaur (1), Nasrollah Ghahramani (1)Affiliations: 1. Department of Nephrology, Pennsylvania state Milton S Hershey Medical Center, United States of America2. Department of medicine-pediatrics, Pennsylvania state Milton S Hershey Medical Center, United States of AmericaCorresponding authorAhmad MatarnehAffiliation: Penn State health , Milton S.hershey medical centerContact: Email ahmadmatarneh99@gmail.comPhone # 717-708-6754Keywords:TMA, Immunosuppressed, transplant

Title Page:Hyponatremia Following CAR-T Cell Therapy in a Patient with Mantle cell Lymphoma, a case reportAhmad Matarneh (1), Sundus Sardar(1), Abdelrauof Akkari (1), Muhammad Abdulbasit (1), Naman Trivedi (1), Nasrollah Ghahramani(1)Affiliations: 1. Department of nephrology, Penn state Milton S Hershey Medical Center, United States of AmericaCorresponding authorAhmad MatarnehAffiliation: Penn State health , Milton S.hershey medical centerContact: Email ahmadmatarneh99@gmail.comPhone # 717-708-6754Keywords: CAR-T therapy, hyponatremia, cytokine release syndrome, Mantle cell lymphoma, renal failureKey clinical message:Chimeric Antigen Receptor T-cell (CAR-T) therapy is used to treat refractory hematologic malignancies. Despite its effectiveness, CAR-T therapy can cause serious side effects, including cytokine release syndrome (CRS), neurotoxicity, and electrolyte imbalances. We report a case of hyponatremia following CAR-T cell therapy in a patient with Mantle cell lymphoma.