Introduction: Radiofrequency Pulmonary Vein Isolation (RF-PVI) is an established treatment for Atrial Fibrillation (AF). Patients are administered Conscious Sedation (CS) or General Anaesthesia (GA) to minimise discomfort and patient movement during RF-PVI. There is a paucity of data on patient experiences of different modes of anaesthesia used during RF-PVI. The purpose of this study was to compare patient experiences of CS versus GA during RF-PVI Methods: A retrospective, observational, single-centre, single-operator study was performed, comparing patient experiences of RF-PVI performed under GA versus CS. A Likert scale questionnaire was used to compare modes of anaesthesia. The domains analysed were: (1) pain/discomfort during the procedure, (2) anxiety/depression post-procedure, (3) satisfaction with recovery time post-procedure, (4) Likelihood To Recommend (LTR) the procedure, (5) LTR mode of anaesthesia, (6) overall satisfaction with the ablation experience. Results: 41 patients were included - 20 in CS group, and 21 in GA group. Groups were well-matched. Patients in the GA group experienced lower levels of pain/discomfort (p<0.001) and were more likely to recommend the mode of anaesthesia (p<0.001), compared with those in CS group. Conclusion: Patients who had GA for RF-PVI experienced less peri-procedural pain than patients who had CS and were more likely to recommend GA as a mode of anaesthesia. This information has important implications for planning service delivery in centres performing AF ablation.