After antibiotics, painkillers are the most common cause of drug allergies. Among painkillers, nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly reported subgroup as shown in many studies. Paracetamol and opioids are among the other most common painkiller allergies. In a study of 2431 unique patients, NSAID allergy was reported in 20.7% and paracetamol allergy in 5.3%.7 Furthermore, a study evaluating adverse drug reactions of NSAIDs emphasizes the frequency of side effects of this drug group other than allergy.15 The NSAID allergy subgroup constituted 52.7% of the 26.7% painkiller allergy group in our study. Moreover, paracetamol was recorded in 19.6% and metamizole sodium (Novalgin®, Sanofi Ilac A.S., Turkey) in 21.4%. We believe that the high prevalence of metamizole sodium allergy, especially in the elderly group, may be related to the frequent use of this drug by primary care physicians in the past.