Drug Allergy: Drugs containing the allergic active ingredient are excluded from prescribing in the HIMS drug order panel. In clinical practice, ciprofloxacins are the first alternative group for patients reporting penicillin allergy. Surgical prophylaxis of patients who report penicillin or cephalosporin allergy is performed with ciprofloxacin due to the risk of cross-reaction. In case of multiple antibiotic allergies, consultation is requested from the infectious diseases clinic, and in case of multiple drug allergies, consultation is requested from the allergy and immunology clinic.