The resulting data, detailing the time to smoking and time to perishing for various weed species and size groups, are presented in Figure 4. A one-way analysis of variance (ANOVA) was performed to examine the influence of weed species on these observed durations. The ANOVA results revealed significant differences (p < 0.05) in smoking and perishing times with respect to weed species, except for the smoking time of large-sized Nutsedge and Pigweed (p = 0.40). As expected, larger weeds required longer exposure times to achieve both smoking and perishing. The average perishing time remained under 30 seconds in all experiments, except for large Pigweeds, which had an average perishing time of 44.5 seconds. These findings underscore the system’s robustness to environmental variations and its effectiveness across a diverse range of weed species, supporting the strategy of tuning laser exposure times based on weed species and size (Figure S2).