Case history
A 35-year-old woman, gravida 2 and para 1, was referred to the Maternal Foetal Medicine (MFM) Unit of our hospital at 9 weeks and 6 days of gestational age (GA) to start the follow-up of her second pregnancy. Her first pregnancy was terminated at 25 weeks of GA because of a fetal hypoplastic left heart syndrome diagnosis. A comparative genomic hybridization-array (CGH) and exome sequencing in trio with the parents was normal. The patient was in good health, except for a Hashimoto thyroiditis, treated with a low dose of l-thyroxine. No other remarkable personal and/or family past history are to be reported.