This study aims to conduct a comprehensive bibliometric analysis of rheumatoid arthritis (RA) and osteoarthritis (OA) research, identifying key trends in scientific output, geographic distribution, and biomarker research to improve early diagnosis and treatment strategies.A bibliometric analysis of 3,295 documents was performed using data from SCOPUS and Web of Science. Key metrics analyzed include annual scientific production, citation counts, Lotka’s Law for author productivity, and country-wise contributions. Biomarkers for early RA detection were also examined to assess their role in advancing personalized treatment.The USA, China, and the UK were identified as leading contributors to RA and OA research, while India ranked 12th globally. Biomarker research emerged as critical for early disease detection, emphasizing its growing relevance in personalized treatment strategies. Collaborative networks and global research productivity were also mapped, highlighting key trends and research gaps. This bibliometric analysis reveals global research trends in arthritis, underscoring the significance of biomarkers in early diagnosis and personalized care. The study provides valuable insights into the evolving landscape of RA and OA research, helping guide future research priorities and collaborative efforts.