Background Over ten years since the first qualitative evidence synthesis (QES) was published in the Cochrane Library, QES and mixed-methods reviews (MMR) with a qualitative component have become increasingly common and influential in healthcare research and policy development. The quality of such reviews and the completeness with which they are reported is therefore of paramount importance. Aim This review aimed to assess the reporting quality of published QESs and MMRs with a qualitative component in the Cochrane Library. Methods All published QESs and MMRs were identified from the Cochrane Library. A bespoke framework developed by key international experts based on the Effective Practice and Organisation of Care (EPOC), Enhancing Transparency in Reporting the Synthesis of Qualitative Research (ENTREQ) and meta-ethnography reporting guidance (eMERGe) was used to code the quality of reporting of QESs and MMRs. Results Thirty-one reviews were identified, including 11 MMRs. The reporting quality of the QESs and MMRs published by Cochrane varied considerably. Based on the criteria within our framework, just over a quarter (8, 26%) of the reviews achieved a score of at least 80%, 18 (58%) required fuller detail in their reporting (scoring between 65%-79%) and 5 (16%) achieved a score of less than 65%. Conclusion This assessment offers important insights into the reporting practices prevalent in these review types and underscores the need for ongoing surveillance. The variability in reporting quality within QESs and MMRs reinforces the need to develop Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) specifically for QES.