Snake bite, also known as snake envenomation, is an injury caused by the bite of a snake, and it can be life threatening if the snake is venomous. Bleeding, renal failure, severe allergic response, tissue death, and breathing problems are all symptoms of chronic illnesses; in addition to the vomiting and the impaired vision, in some cases, tingling in the limbs and sweating can be seen. Snake bites are a serious health, social, and economical danger in many regions of the world, especially in the tropical and subtropical countries. The agriculture sector has the greatest occupational risk in terms of snake bites. High mortality is largely caused by inadequate health care, poor transportation facilities, and delays in administering the anti- venom, particularly in remote areas. The families, Elapidae and Viperidae contribute to the most common snake bites. The Indian spectacled cobra (Naja naja), common krait (Bungarus caeruleus), Russell’s viper (Daboia russelii), and saw-scaled viper (Echis carinatus) are the most dangerous snakes in India. The venomous effects are from a complex mixture of proteins- enzymes, nonenzymatic polypeptide toxins, and nontoxic proteins. Depending on the nature of toxin and the type of snake, the toxins are classified into neuro, cardio, and cytotoxins. This review aimed to present more perspectives regarding the venomous snakes in India, the mechanism of action of snake venom.