Key clinical message
This case report presents a preadolescent female with a rare presentation of lupus as isolated chorea. An investigation to find out the cause of unexplained cytopenia with raised inflammatory markers ultimately led to the diagnosis of neuropsychiatric lupus with antiphospholipid antibodies. Lupus should always be included in the differential for chorea in children.
Keywords: lupus, chorea, paediatrics, neuropsychiatric lupus.