not-yet-known
      not-yet-known
    
    
      not-yet-known
      
      
        unknown
      
    
  
  
    Introduction: Evidence from multiple data sources indicates
that toxocariasis might play a role in the allergic asthma in children.
This case-control study investigated the connection between
Toxocara seropositivity and allergic asthma. It also sought to
identify the conventional risk factors associated with both asthma and
Toxocara infection. Methods: In this case-control study,
200 allergic asthma children, and 208 children with no history of
allergic asthma were included as the healthy group. Sera samples were
examined for specific anti-Toxocara IgG antibodies using a serological
assay. Results: The overall prevalence of toxocariasis was
6.9% among children. The seroprevalence of toxocariasis in asthmatic
children and healthy children was 8% and 5.8% respectively, with no
significant difference (P-value= 0.373). In subgroup analyses based on
sociodemographic, Toxocara infection seropositivity was significantly
associated with two independent variables, including the father’s
occupation (P-value = 0.017) and soil contact in asthmatic children
(P-value = 0.033). Conclusions: Our results showed a higher
prevalence of Toxocara infection in asthmatic children compared to
healthy controls, but this difference was not statistically significant.
To gain a clearer understanding and comparison of Toxocara infection
rates between asthmatic and healthy children, additional comprehensive
studies with larger sample sizes and diverse detection methods using
different antigenic sources are required.