ABSTRACT

Infective endocarditis (IE) is a serious infection of the heart valves and endocardium, most commonly affecting left-sided valves, though right-sided infective endocarditis, particularly of the tricuspid valve, is increasingly reported, especially among intravenous drug users and patients with implanted cardiac devices. This report presents the rare case of a 31-year-old female who developed tricuspid valve infective endocarditis following a septic abortion. The patient had undergone a medical termination of pregnancy at 16 weeks gestation and was treated for an incomplete septic abortion with manual evacuation and intravenous antibiotics. Despite initial treatment, the patient returned with persistent fever, chills, and mild vaginal bleeding. Blood cultures confirmed methicillin-resistant Staphylococcus aureus (MRSA), and echocardiography revealed vegetation on the tricuspid valve, confirming the diagnosis of IE. The patient was treated with a combination of broad-spectrum antibiotics, including piperacillin-tazobactam, vancomycin, and gentamicin, along with supportive therapies. The case highlights the importance of considering IE in patients with septic abortion, particularly when fever and infection persist despite treatment. Early recognition and management are crucial to prevent life-threatening complications. This case underscores the need for multidisciplinary management and adherence to best practices, such as antibiotic prophylaxis, to reduce the risk of infection in gynecological procedures.