Given the critical role of the oral and maxillofacial regions in human function and aesthetics, oral health significantly impacts patients’ quality of life, physical health, physiological and psychological well-being, and aesthetic perception. Challenges arise due to the complex anatomy and limited efficacy of conventional treatment approaches. Phototheranostics, represented by photodynamic therapy (PDT) and photothermal therapy (PTT), has garnered heightened attention and utilization due to its advantages. PDT and PTT offer several advantages, such as being highly selective, non-invasive, cost-effective, having reduced side effects, and minimal drug resistance. However, despite these benefits, there is a need for improved photosensitizers and photothermal agents to enhance their efficacy in treating oral diseases. The discovery of aggregation-induced emission (AIE) has ushered in a new direction for research on PDT and PTT. Treatment of oral diseases can be considerably aided by AIE’s high luminescence yield, biocompatibility, photostability, and positive correlation. This review highlights recent advancements in AIE luminogens (AIEgens) as a promising phototheranostics tool in oral healthcare, focusing on their applications in teeth whitening, oral infectious diseases, and oral cancer. Additionally, we address the challenges and future directions to accelerate the clinical translation of AIEgens.