Megan Jayne Ralston

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Pediatric Eosinophilic Granulomatosis with Polyangiitis Complicated by Chronic Steroid UseMegan Jayne Ralstona, MS, and Edward Johnsonb, MD,Affiliations: aChildren’s Hospital of the King’s DaughterAddress correspondence to: Megan Jayne Ralston, Department of Pediatrics, Children’s Hospital of the King’s Daughter, Norfolk, VA 23510 [ralstom@odu.edu], 7742389377.Short title: Pediatric EGPA Complicated by Chronic Steroid UseConflict of Interest Disclosures: The authors have no conflicts of interest to disclose.IRB Approval: IRB approval for case reports is not required by our institution. Verbal consent was obtained from the patient and their parents.Funding/Support: No funding was secured for this study.Abbreviations:HES - Hypereosinophilic syndromeEGPA - Eosinophilic Granulomatosis with PolyangiitisGI - GastrointestinalCS - CorticosteroidsOCS - Oral corticosteroidsCXR - Chest X-rayCT - Computed TomographyPFT - Pulmonary function testingRP2-PCR - Respiratory Pathogen Panel PCRANCA - Antineutrophil cytoplasmic antibodiesp-ANCA - Perinuclear antineutrophil cytoplasmic antibodiesPR3 - Proteinase 3MPO - MyeloperoxidaseWBC - White blood cellsPSL - PrednisoloneCBC - Complete Blood CountFeNO - Fractional exhaled nitric oxidePICU - Pediatric Intensive Care UnitKeywords: Pediatric Eosinophilic Granulomatosis; Polyangiitis; Chronic Steroid Use; Vasculitis; Pediatric Autoimmune Disease; Steroid ComplicationsArticle SummaryExplore the complex diagnosis and successful treatment of a rare case of pediatric Eosinophilic Granulomatosis with Polyangiitis (EGPA) in an 11-year-old boy.