J.F. performed the experiments with technical assistance of M.B. and W.F.J.v.IJ. J.F. performed data analysis. R.W.H., and R.S. supervised the project and participated in experimental design and technical discussions. J.F. wrote the first draft of the paper. J.F., R.W.H. and R.S. drafted the final manuscript, which was approved by all co-authors.