A document by Sandesh Shah. Click on the document to view its contents.

Not All That Spreads is Sporotrichosis: A Leprosy IllusionAuthor names and Affiliations: Sandesh Shah1, Joshana Shrestha2, Mohan Bhusal1, Deepika Neupane1, Radhika Maharjan3Senior Dermatologist, Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, NepalResident Doctor, Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, NepalResident Doctor, Department of Prosthodontics, B.P Koirala Institute of Health Sciences, Dharan, Nepal

Title: Rheumatoid Neutrophilic Dermatitis in Early Rheumatoid Arthritis: Expanding the Spectrum of Cutaneous Manifestations

More Than Just a Plaque: Primary Cutaneous Localized Nodular Amyloidosis Masquerading as Common DermatosesAuthor names and Affiliations: Sandesh Shah1, Joshana Shrestha2Lecturer, Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, NepalResident Doctor, Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal

IntroductionPityriasis lichenoides et varioliformis acuta (PLEVA), also known as Mucha-Habermann disease, is a rare T-cell lymphoproliferative disorder that can occur at any age but most commonly affects children and young adults, with a slight male preponderance.1 The pathogenesis of PLEVA is thought to involve two mechanisms: a T-cell dyscrasia and an aberrant immune response to viral, bacterial, or protozoal infections.2PLEVA is marked by the sudden appearance of asymptomatic to multiple small erythematous papules that rapidly progress into polymorphic lesions with varying forms, including vesicles, pustules, hemorrhagic crusted papules, and shallow ulcers. These lesions typically resolve within weeks to months but can occasionally leave behind long-lasting complications such as hyperpigmented or hypopigmented, varioliform scars. The lesions primarily affect the anterior trunk, flexural areas, and proximal extremities, though they can also occur in other parts of the body, sparing the mucosa.1,3PLEVA typically has a self-limiting course, with lesions resolving spontaneously over time. However, in certain cases, the condition may persist and follow a more recalcitrant trajectory, characterized by recurring flare-ups and varying lengths of remission between episodes.3To our knowledge, this is the first documented case of PLEVA presenting with significant facial and mucosal involvement in a 15-year-old male from Nepal. This case highlights the atypical nature of the condition and underscores the rarity of such presentations.

Author names and Affiliations: Joshana Shrestha1, Mohan Bhusal2, Smriti Piya1, Rabin Baniya1, Sanjay Dhungana3.Resident Doctor, Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal.Lecturer, Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal.MBBS Student, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal.Corresponding author:Joshana Shrestha,Nepal Medical College and Teaching Hospital, Kathmandu, NepalEmail: joshana.shrestha1996@gmail.comOrcid ID: https://orcid.org/0009-0000-5570-189XOther Author Details:Mohan Bhusal, Email id: bhusalmohan1@gmail.com , Orcid id: https://orcid.org/0000-0003-3122-2346Smriti Piya, Email id: simplysmritee@gmail.com, Orcid id: https://orcid.org/0009-0002-8408-7547Rabin Baniya, Email id: baniyarabin1357@gmail.com, Orcid id: https://orcid.org/0009-0009-7761-6552Sanjay Dhungana, Email id: sanjaydhungana2000@gmail.com, Orcid id: https://orcid.org/0009-0000-9776-0361Total number of pages: 18Total number of photographs: 7Total number of tables: 1

Dyshidrosiform Bullous Pemphigoid with Dermatophyte infection: An association or coincidence? Diagnostic challenge of a case and review of literatureKeywords: Dyshidrosiform Bullous Pemphigoid; Heart disease; Dermatophyte infection

INTRODUCTIONPsoriasis is a chronic papulosquamous skin disease that has a prevalence ranging from 0.1% to 1.5% and may present at any age.1Its rare variant, juvenile-onset pustular psoriasis, is a recalcitrant disease with a unique immunopathogenesis and morphology, unlike its more prevalent plaque-type counterpart and is often resistant to conventional systemic therapy.2, 3Methotrexate is a drug that has cytotoxic, anti-inflammatory and immune-modulatory activities that provide clinical benefits in the therapy of psoriasis.4