Abstract
Hematopoietic stem cell transplant(HSCT) is the only modality that, if
performed in the early- stages of cerebral X-linked
adrenoleukodystrophy(X-ALD) can lead to good outcomes. Loes- score,
calculated based on the findings of the magnetic resonance imaging(MRI)
of the brain, helps in the selection of patients for HSCT. As per
recommendations, the Loes-score should be <10 for a patient to
be eligible for HSCT. Here we report a child of cerebral X-ALD with Loes
of 12, but a good neurological function score(NFS), who was treated with
HSCT, and had good outcomes. It is therefore important to utilize other
parameters along with the Loes score, in selecting patients for HSCT in
X-ALD.