Ethics Approval Statement
The European VALHUDES study (ClincalTrail.gov: NCT04312737) was conducted under the Declaration of Helsinki. The study was approved by the central Ethics Committee of the Coordinating Centre, ASST degli Spedali Civili di Brescia, Brescia, Italy (Ethics approval number: NP 3879- Studio WP6-HPVONC) and subsequently by the local Ethics Committees of the other participating centres. All women signed a written informed consent form before to enrolment.