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Recent Advances of Terpenoids with Intriguing Chemical Skele-tons and Biological Activities
  • +2
  • Yi Zang,
  • Ruonan Sun,
  • Ranqi Feng,
  • Honghui Zhu,
  • Xu-Wen Li
Yi Zang
Guangdong Academy of Sciences
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Ruonan Sun
Chinese Academy of Sciences
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Ranqi Feng
Chinese Academy of Sciences
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Honghui Zhu
Guangdong Academy of Sciences
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Xu-Wen Li
Shanghai Institute of Materia Medica CAS

Corresponding Author:xwli@simm.ac.cn

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Abstract

Terpenoids are the largest and diverse family of natural secondary metabolites that have attracted more attention from chemists and pharmacologists for their intriguing skeletons and broad biological activities, including anti-inflammatory, antitumoral, antimicrobial, and anti-viral effects. Based on the previous reviews, we did a comprehensive summary of recent advances of bioactive terpenoids, focusing on their intriguing structural features and promising biological activities, covering the literatures from 2020 to 2023. In this review, 543 terpenoids with remarkable chemical architectures and biological properties are classified as monoterpenoids (7), sesquiterpenoids (142), diterpenoids (129), sesterterpenoids (24), triterpenoids (52), meroterpenoids (167), and miscellaneous terpenoids (14), that were isolated from terrestrial and marine resources. This review would provide a reference for researchers to rapidly discover the interesting terpenoids for further study as promising drug leads
30 Jun 2024Submitted to Chinese Journal of Chemistry
11 Jul 2024Submission Checks Completed
11 Jul 2024Assigned to Editor
11 Jul 2024Review(s) Completed, Editorial Evaluation Pending
19 Jul 2024Reviewer(s) Assigned
08 Aug 2024Editorial Decision: Revise Minor
06 Sep 20241st Revision Received
07 Sep 2024Submission Checks Completed
07 Sep 2024Assigned to Editor
07 Sep 2024Review(s) Completed, Editorial Evaluation Pending
09 Sep 2024Reviewer(s) Assigned
14 Sep 2024Editorial Decision: Accept