Statistical Analysis
All data are presented as mean ± standard error of the mean (mean ± SEM) of n experiments, where n corresponds to the number of independent observations. The statistical significance of the differences was assessed using the Student’s t-test, One-way ANOVA, or Two-way ANOVA as specified in the legends of Figures and Tables. Statistical analyses were performed using GraphPad Prism 8.0 (Dotmatics, Boston, MA, USA) or the SigmaPlot 15 (Inpixon HQ, Palo Alto, CA, USA) softwares. Differences were considered significant when P<0.05 (two-tailed).